In today’s rapidly evolving global economy, job stress has emerged as a more pervasive issue than ever before. Conventional perspectives often link job stress primarily to work-related conditions, Yet underexplore the significant role of non-work dimensions. Personal life conditions are central to individuals’ identities and often spill over into their professional domains. Recognising the profound impact of these interconnected domains on job stress is essential. Addressing this gap, the present study examines the influence of personal and familial factors on job stress. Data were collected from 140 banking professionals in Sri Lanka using a structured survey questionnaire. The responses were analysed using Partial Least Squares Structural Equation Modelling (PLS-SEM) to test the hypotheses. The results indicate that the majority of employees experience a high level of job stress. Further, Individual Well-being, Personality Traits, and Domestic Support respectively emerged as key contributors, which collectively explained approximately 33% of the variance in their level of job stress. These insights support employees, HR managers, policymakers, and researchers in advancing occupational health and performance.